Health & Living, November 3, 2010
On October 14, the World Health Organisation (WHO) launched the first ever global report on neglected tropical diseases titled: Working to Overcome the Global Impact of Tropical Diseases
NTDs are diseases that thrive in tropical areas and are closely linked with poverty. They are ancient diseases that plagued humanity but have since disappeared from most parts of the world save for those areas that are poor and are within the tropics.
Because they affect poor, disadvantaged people who have neither the resources nor the voice to draw attention to the diseases, they are usually ignored at both national and international levels. Yet some of the diseases are fatal, and sometimes maim their victims.
They also render the affected people less productive, perpetuating poverty amongst the affected communities and the countries in which these people live.
Given that the diseases impede poverty reduction, one of the Millennium Development Goals, WHO has moved to eliminate them by 2020 through scaling up interventions against them.
The interventions include: preventive chemotherapy (immunisation), using better, safer and simpler diagnostic methods and decentralising clinical management so that affected communities access treatment, among others.
NTDs in Uganda
The World Health Organisation lists 17 neglected diseases: Human African Trypanosomiasis (sleeping sickness), elephantiasis, river blindness (onchoceciasis), bilharzia, leshmaniasis (kala-a-za), trachoma, Buruli ulcer, plague, intestinal parasites, dengue, leprosy, chagas disease (American trypanosomiasis), guinea worm, foodborne trematode infections, echinococcosis, cysticercosis, and rabies.
Of the 17, Uganda is encumbered with the first nine. Dr. Dawson Bob Mbulamberi, the assistant commissioner for Health Services at the ministry of Health says that so far, Uganda has managed to eliminate guinea worm, meaning it is capable of meeting WHO’s target of eliminating the nine NTDs that affect Uganda by 2020.
NTDs with no tools for control in Uganda
The diseases, sleeping sickness, kala-a-za, Buruli ulcer and plague are a problem because so far, there are no tools or strategies mapped for their control.
Sleeping sickness
Today, 10 million Ugandans are at risk of catching sleeping sickness and cases are confined to south-eastern Busoga, Tororo, Busia, Mbale, Mukono and some parts of Kayunga. Recently, cases cropped up in the Lango-Teso sub-region as a result of infected cows having been transferred from Kamuli to Teso.
Sleeping sickness is spread by tsetse flies. Tsetse flies, which have a preference for human blood, can pick parasites from sick animals and transmit them to people as was the case in Busoga. The West Nile sub-region, which includes Arua, Yumbe, Moyo and Adjumani also harbours cases of sleeping sickness since 1981, when Ugandan refugees, who had fled to Southern Sudan after the fall of Idi Amin returned with the disease that was common in Southern Sudan.
The West Nile sub-region has the chronic type of sleeping sickness which presents no symptoms until a year after infection. Meanwhile, Busoga sub-region has the acute type of sleeping sickness which brings fever and headaches. Sleeping sickness, unlike other NTDs, easily kills. If one gets infected, it is advisable to get treatment immediately.
Leshmaniasis (Kala-a-za)
Kala-a-za, which is spread by sand flies found in forests, caves or burrows of small rodents, presents itself with a fever, swollen lymph nodes and swellings. It mostly affects the skin, causing lesions which can disappear after some months, leaving scars; sometimes, the lesions are chronic.
This disease, a big problem in Kenya, affects only one county in Uganda, Pokot County in Amudat district. Since the Pokot of Uganda are in the habit of visiting the Pokot of Kenya, they pick it from there.
Dr. Mbulamberi says because such a disease is localised, it is difficult to draw attention to it or even make government commit resources because the unaffected cannot comprehend it.
Buruli ulcer
Buruli ulcer is caused by a germ that affects the skin. It presents itself with a big wound on the skin, which usually starts out as a swelling, though sometimes the wound can dig deep till it gets to the bones.
In Uganda, cases have been recorded in only Sembabule district though it is said that further research could present cases in other parts of the country. The fact that people who usually suffer from NTDs are isolated means it is hard to register cases.
Plague
Plague, which is spread by fleas, presents itself with flu-like symptoms at the onset and these are followed by chills, fever, headaches, body aches, weakness, nausea and vomiting. In Uganda, it is found in Nebbi and Arua districts. It has been hard to control because of porous borders between Uganda and the Democratic Republic of Congo (DRC). Plague is transmitted to Uganda from DRC.
NTDs under control in Uganda
Uganda has made some progress with elephantiasis, river blindness, bilharzia, intestinal parasites and trachoma.
Elephantiasis
Fourteen million Ugandans, especially those in Northern Uganda, are at risk of catching elephantiasis. Elephantiasis is spread by the culex mosquito and it presents itself with endema of the breasts, vulvar (this is for the women and a woman with this disease leaks from the vagina and gives off a foul smell).
The men suffer hydrolysis (mpanama). It is dangerous in that it has the potential to end marriages. Dr. Mbulamberi says that the infection, which one catches when still young, only manifests in early adulthood (20-25 years), a time when people are getting married.
Now when a man’s private parts are affected by hydrolisis or a woman’s vulvar is affected, the marriage disintegrates because the young woman or man cannot remain married to someone who is sexually incapacitated.
River blindness (onchoceciasis)
River blindness is spread by the black fly and it mostly affects individuals near fast running water bodies or those that live in swampy areas. People in Fort Portal and Mbale are the most affected by this disease though 2.6 million Ugandans are at a risk of catching it. Apart from causing blindness, river blindness can also destroy the patient’s skin giving it a “monitor lizard skin” look.
Intestinal parasites
These are rather common and symptoms include diarrhoea, foul breath and circles under the eyes, among others. Anyone can catch them and almost everyone has them though they only become a threat when too many of them exist in the body.
Trachoma
Trachoma mostly afflicts people in Busoga and Karamoja. It is a disease that thrives in areas with poor hygiene. It is spread by flies; individuals usually get infected when they are young. If not treated, it can result in blindness later in life. Seven million Ugandans are at risk of catching it.
Actions Uganda has taken
Elephantiasis, river blindness, intestinal parasites and trachoma are under control. One of the tools used to control these diseases, with the aim of eradicating them within five or six years, include preventive chemotherapy where drugs are given out once a year to affected communities.
Because the affected are poor, they are usually treated for all the NTDs that affect them on the same day so they do not waste meagre resources moving to and from the treatment area. Some efforts are being made to treat those diseases for which interventions have not been found.
Health centres were set up in areas like Iganga, Kaberamaido, Adjumani, Tororo to avail treatment to those affected by sleeping sickness. Screening services are also at hand at the health centres to test those that suspect that they have sleeping sickness. Kala-a-za is also being treated.
The department of Pathology at the College of Health Sciences at Mulago Hospital is carrying out research on Buruli ulcer. The Uganda Virus Institute is in charge of research and control of plague.
Challenges
Dr. Mbulamberi says the challenges faced in fighting NTDs include the indifference to the diseases because they affect people who are not so visible. As such, it is difficult to have resources committed to fighting the diseases. Also, members of the affected communities sometimes do not care to get treatment.
– last update:4 November 2010